Juvenile polyposis coli.

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Juvenile polyposis coli.

The term 'polyposis coli' applies to a condition of multiple polyps of the large intestine and is used synonymously with 'familial polyposis' and 'multiple adenomatosis'. The latter name emphasizes the fact that the individual polyps of this disease in no way differ from adenomas observed as solitary lesions. The object of this paper is to describe the histopathology, clinical features, and fam...

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Juvenile polyposis coli.

A FEW decades ago intestinal polyposis was regarded as a single entity, but increasing knowledge has led to the identification of a number of different syndromes. The term polyposis coli is usually taken to mean familial adenomatosis coli, a premalignant condition occurring in adolescents and adults. Although there have been many reports of colonic polyposis in children, discussions on the subj...

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A Case of Juvenile Polyposis Coli

80 Our patient is a 20-year-old white female who presented with a two-year history of intermittent rectal bleeding and iron deficiency anemia. She had no significant family history. A gastroenterologist initially evaluated her two years prior to the current presentation. In preparation for a scheduled colonoscopy at that time, she left the facility against medical advice because of difficulty i...

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Familial juvenile polyposis coli; increased risk of colorectal cancer.

Six patients from one family and one solitary patient with juvenile polyposis coli are described. The histological changes in colonic polyps formed a spectrum from juvenile polyps, through focal to extensive adenomatous change, to adenocarcinomas. One patient aged 49 years had an adenocarcinoma of the colon and in another, aged 33, with rectal polyps and metastatic cancer this was suspected alt...

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Juvenile polyposis syndrome

Juvenile polyposis syndrome (JPS) is an autosomal dominant predisposition to the occurrence of hamartomatous polyps in the gastrointestinal tract. Diagnosis of JPS is based on the occurrence of numerous colon and rectum polyps or any number of polyps with family history and, in the case of juvenile polyps, their occurrence also outside the large intestine. The JPS is caused by mutations in SMAD...

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ژورنال

عنوان ژورنال: Journal of Medical Genetics

سال: 1966

ISSN: 1468-6244

DOI: 10.1136/jmg.3.1.5